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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18368e0b44db1b5d62db9a0991f94d066738f1c8ad26c62b96de9b1639c0fdc4' 
  AND token = 'FOAjNeoH1QkOfgrKBJhEpo15zLoUQpaKyBGyHaD7IrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}