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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d989398c8582d61d832217805bf5a4a798a133fff7b65eba058a2a066dc8def' 
  AND token = 'kJrhaRQ0oZkh62+A6w9fRep7IsmTd1J2rCdLWkEhY8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}