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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '32349ca3d1f929fa9524df1be9155205fa433da513f52681cb9791c846be3f5b' 
  AND token = 'CxdibYqudhFAfoMkKRK0dt+GlR4uN+FQTn7Zh9Mp2cg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}