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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '395cf63e89b2d66322636502c0b9d920507e4a538ee1ae59e769566905ce9520' 
  AND token = 'mUZ7M8tQ78qCjQZTDYmskm7rTwOVYqIYF7WLYLtUVuo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}