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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a49ce41a7bedc9e9243b6506b5e1c0b1b0e4000bbd78b638d2fea3729a43774' 
  AND token = 'N/1WQ5X2JnebiI2NL0fV1acFTkkwXCbJf0Hec60MOvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}