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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5342246b3fbdefe53e9927d0d98b75c5388372c072a0aa6cc011fc33e7562e14' 
  AND token = 'ERU3b7qF2QXsv3m0on7gzk2rqeqiL7OprjVG4OWPgBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}