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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ea8c50146f1b49e612315bca6d14e73555990ef942a74528d08aa5ab5adf5f0' 
  AND token = 'mUSdlqpUxjIJTWwyJM4wT+DJRnPdG+WQz5Ee27UivWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}