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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3877b97c99df87f6699365daa77e20d96a931bae916830b39a490a3171d00658' 
  AND token = 'bzUTBG3E1wB8UjX0CRFoqRUZwTDysI4hhRPc/18Cras=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}