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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '685e14fbe179be70e4ab14da2fd8acca9b1b1b46e809e7ad2796d63309b5816a' 
  AND token = 'bppz+I6jij0G25ylE0t0MvKn9w2fSzdsw8S9vFiIEFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}