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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '680d5ac0b0df09262cb0194c2d3f6ebcb655e6a30c799766d60325dbad8af2e0' 
  AND token = 'tOFL9jW9M0LT557GKphLrjH4p7SensTEmLdL5Tr9mX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}