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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e55a523a7c790e166cc8b0a600d40039df83f081dec8f7e80e9dd4035e019407' 
  AND token = 'HPL2VVtN53luxJAtNFQnXYuCNG3Co9F8/grpFbS43Ac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}