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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78f2e424cefb430a347f3c1fa2000d433e34b218a245808affebd07e224c0312' 
  AND token = 'RkiSR5sAyFAYmSNfUajUvC3fqnTtHQlb8mapyYghb2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}