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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca886d62a2981bb301fd296d9beafa4346d529400e566b62b4cd3366bbceec63' 
  AND token = 'vOWzpD+H35hncmIIUQ4GpH+NtA6HJpQ3oxG1inHPgxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}