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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85ca80aa164d777ae0972e8296792169be6205d14f02308e1baf147a8de479e6' 
  AND token = '8cjKh3IAXkupuImslPXK8e5+8uVHTDKhctvRjBAyCMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}