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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5545c21e0ceb9830e7d2399a1ea9df245da6f265f1ee341e266b69c2b2fa7e17' 
  AND token = 'w+C5pNus2Yy/NAhoENFlI1yGgax/RBUBVl2N5ovHBmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}