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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd3641c17b26e3c64af7af77de182e8732d02825accfbcd41324aa7b4b33af4a' 
  AND token = 'e88Txres2mE1n3S5AeDSKeDxOVh0R0MlGjL3NChV2Ao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}