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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '681746e06239013455b3774193b1fa1c531548ba74c219673d5cfddca900f05e' 
  AND token = 'PORlgqNdyXK36YYW7tV6REKMi4b15J+hDgi6nouRHdI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}