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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc14093ddde90268c0d3d2d0ef0cc3351e3a8e3c48fcfb1068444874f420939c' 
  AND token = 'ZvtIlcvgCsWJem4CZjDavwlfexA5Ql9AHfTKGjQtbBE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}