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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce3258d45af6db23f70f53b65247b6af9bf5ea976d3fd5016714d13df0172dc0' 
  AND token = '+v6Eea8xuk7z8jebvz2mKdf2ASiUp80RqWtiF3SH5kY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}