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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0432ffb4e5bd7a75d19d96679c920b49129edff3619bf83b56c4bafc14edabcb' 
  AND token = 'h+y5WEMRWAHs0WnSsXe9L8KX9XB8YxuQfdNWFIHHLRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}