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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5d8065d71a0fdc32724da10a11c09f8c405f87dac9f35c792c59431a1a70917' 
  AND token = 'wqU8dtp3AO9XPKJbbD/tFTb61dAqhNThh226gfG6MIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}