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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f6378ee7ef5e25e53a4383d5e22cc2e35d407bc0734be73524fd1e814f2a22e' 
  AND token = 'VO4sihIDli66Qg/6GvHjGiu0JhE79EsNkeRQ5+eixFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}