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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d37a2031c8c84a5704888bb10e304d6a93abd7b3ff021b3bb9ac145d30978ce' 
  AND token = 'sXwcAGoJUofgmTz0V+P5N1JJVW3udzf0aVvcQIVZQv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}