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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4cc0de7869427200898ec53e97ce35960f298bc3d4d1f7e46a1716119279abd' 
  AND token = 'X0DP3EdNpXxx9ITuaIecZKdgXLU4crNdvxkInQGJ5Vs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}