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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e35fcdf3a127cee89a35e9ce0d81b2576f1e363561c815b38d9e2792d9c7f44d' 
  AND token = 'E0zoRxq2WZqC7z5GqhPUeOuEv2eZ8652cDTxQKzw/Q4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}