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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53a1b04f0d160f730da7dcfaf258d27c2fa02a608b5afd9c579242d1b3503997' 
  AND token = 'l29RM7qaDW/z8BEbeX4x1gZ100EIDdIOde84L9fYcCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}