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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49a489b5f4cf103987f6fd29a7a92e718cffcff5650ea6f37137f525499cfff9' 
  AND token = 'H8uL7h90iQTQesHeL5ba/0+iWOdw2tR0yPdUZ/+pbqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}