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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fef7d15d085e9a2948e2e942332c431a76db61d627b8bd171a89fc5bdc18001e' 
  AND token = 'a7ZqZl8E0CLHR0JUfyFebVpwHvlEf3cLScOr8b27fIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}