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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25c60c44d804719653e57623a157a09e0948ea1b5d54af91b43e365e3557ead7' 
  AND token = 'CoawnhXDmNLg4fR5OcewDo70iznsF9Dx1c7tG25Bzso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}