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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4886745547366b37d1e8ae8691b8af3c2af8362d21bcffe1837fd4c0f6c76725' 
  AND token = 'qAFX/MPQVskdGPf8f8zwzNrLipJCMWO5VkO8EcN9j6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}