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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6b6d7db56b4ddc40b77102d87ea414e58221d3b91e30cff66fa00410932b51b' 
  AND token = '+YuJAXgLrD3NB1Y94OeGF+EMxNeNIF7ln/XOj9RH6Hs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}