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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c961080252699280b0052b2570ad4359ab8e4c48e040a3da4c182ab687d63ca' 
  AND token = 'hzt0Z4nqhIw8O6NxjAN/8seMY95vjGDfv/1W7+0ubTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}