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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a62ecf4b09a1390033b0052c7c16df9f270f0312993450f0bf13a9489329e2a' 
  AND token = 'Rf9LJWN3Hvu155dFrRZzVIs4Axv3kCzDuho/2HkFJT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}