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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75b3748b860371a296cca81948e094df11fb1f2790fd1ec4771b34571e70d00d' 
  AND token = 'eeilvucUuPz1zKIdE4lqGfNRgYlhQPStyrEa52y2prM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}