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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8133ebaacb6c6483b3c21259f51be554f96f12c000adf5dd279e0ca14831b921' 
  AND token = 'gy9jSTATS8kgpWtgrZ+2aiL/KEpaDd64MjdT8SOn53w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}