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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '982a6e6502dc40eeb8a16f310e0573c0f61c4eea601bdfe2da14e8aa90467211' 
  AND token = 'zpYjvLYHUst69D4oZHL4jnu1SizxFTs5GfdJzn8/xXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}