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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8c49c4bf748c3a3d0770ce1bb1d89e3c383e29096e0044cbfa96d465f78fde3' 
  AND token = 'w/UImQK0+xBJW9WkvcfLkvxRNsbEAhS9wh/Gpd95s4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}