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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e2c460108e874ba63b0c34d8724db65563dcddb757606164979368d159a32f0' 
  AND token = '3lySa45xM6UVXUA3qO1X471P+XXWbeCmN+cV+aL9u/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}