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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd17c257cbf2ab14d47a76e82d5aa681ca75255b8c945c19631a9dfe580e3950c' 
  AND token = '4FEIQjJMqfToZlrjs6lG2LaT35SjwAEHjNJZjsykSRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}