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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '381ea5cbe5ae4834d069448f1f9d3873cc80b38d292215690e7b12913b2b6bdf' 
  AND token = 'SRIQ+lvLrGoHX5g4AZu/RHl6Wb+o5YgmaWL64hG1eLI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}