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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f41f6127a0a8df11a7df2bb95faa8a4ee3db2a3913f1147f25ab82c45d782161' 
  AND token = '6vP7RGuaSfcfcDmLdVVi7NtiOSh9yOaL5GNyBZNWB6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}