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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e66889bad268fddddfa22c8f4f9b3309e9e02e5aee72e1e021b2b12b5fc3efe' 
  AND token = 'ovuzTrMhXKApoBlR/gekUrhU9/Y1tMIv+nHFNSCGe6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}