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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24c721d40fcca9a0156a8db8fdf67cbb4b60cf3ef7c81f3444588e68ea474bb7' 
  AND token = '5b178rSsgSc9m9nkq2MzJrIOvv/d2M+/tMY3x3N1PY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}