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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef7da3e29016f924b91373e753a73c0fa9a6a05018d5e73ecf600d8566a10860' 
  AND token = 'v+GGk1z8aNFFWsPVUjmnelJfWYoia7gICxLi/1cW4e0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}