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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a894e13010d58b4660e7d0f275d1b4326befd36f20c166f566225eaae0f0ea33' 
  AND token = 'Ub2VJo1oY4xEestVJ5Q/MK6V617qp9IfQQMQgp2BnC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}