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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1a59cdf543b5bad9bffea6f68e0d79d84125ad19a0e184502c82c5f9eddb04c' 
  AND token = 'lsEG/rbo2y5TSpq7oD2XI/1+rGKcI9F7ihsgyC/JUE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}