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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6398760276d295453c8c090cc096a01c9e6a1fedc6b105ce8fca07d0324033bc' 
  AND token = 'CqYQmXFyf1WmUPsgmlUjkj9YGA1pm7XJJDUQfpf+TkA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}