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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e0d309f4122f97fa4c9cf8d2fcb98478eb665ef0fc006dfe536edf0dd94f211' 
  AND token = 'qukD/8++FkzfMBjsqZh0AvlFIXMm8oCs2p9hn7Akm0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}