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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c22398e3680899afb19506bf25ecf9ec32b567bcc58a23c04d40007aae6ea0f2' 
  AND token = 'w5D1MjDHKn0oaX2KcmegKr2ZjFU3A+4Ad5QHS4q7I2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}