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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78266900682098387c5ac441cd89a07073d0ce47ada24aef95963ab59361d849' 
  AND token = '+91iZP+j9Uzvk+bSbtkft9BJ2jI8uEE2nN6aFpaY5Sg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}